T cell Specialisation

Topics Covered:

Haematopoietic Stem Cells - Lineage

Cytotoxic T Lymphocyte Subsets

T helper Cell Subsets

Immune Homeostasis Tregs activities for TME

TCR / CD3 Complex with CAR architecture

Tumour Micro Environment - TME Myeloid-Derived Suppressor Cells (MDSCs) & M2 Macrophages

Cancer Associated Fibroblasts

Hot Tumours and Cold Tumours

Engineered TGF-β receptors

CTLA-4 and CAR T Architecture

MHC Downregulation and NK Cells

The video is available here: T cell Specialisation

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Case Study Milestone 2 FD Part 2 - Development Plan