Theory and Principles of CAR T Cell Therapies: Structures and Design
Basic Principles and Design Aspects of the CAR in T cell therapies
Chimeric Antigen Receptor - T cells: CD4+ and CD8+ Cytotoxic Cells
Clinical Development: Synthetic Receptors
Basic CAR T-cell Structure
Antigen Binding: Key Target Antigens in clinical trials and development.
CAR T-cells Today
Antigen Density
Avidity and Affinity
Hinge / Spacer
Fc Binding
TGN1412 Trial Disaster
Transmembrane Domain
Signalling Domain
1XX CAR design
Co-stimulators
Background Information
References